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Abstract
Clouds are rapidly joining high-performance computing systems, clusters, and grids as viable platforms for scientific exploration and discovery. As a result, understanding application formulations and usage modes that are meaningful in such a hybrid infrastructure, and how application workflows can effectively utilize it, is critical. Here, three hybrid HPC, grid, and cloud cyberinfrastructure usage modes are explored: HPC in the Cloud, HPC plus Cloud, and HPC as a Service. The article presents illustrative scenarios in each case and outlines benefits, limitations, and research challenges.
Overview: Hybrid HPC and Cloud Usage Modes

Citation
Manish Parashar, Moustafa AbdelBaky, Ivan Rodero and Aditya Devarakonda, “Cloud Paradigms and Practices for Computational and Data-Enabled Science and Engineering”, Computing in Science & Engineering, 15(4), pp. 10-18, 2013. https://doi.org/10.1109/MCSE.2013.49
@article{parashar2013cloud,
title={Cloud Paradigms and Practices for Computational and Data-Enabled Science and Engineering},
author={Parashar, Manish and AbdelBaky, Moustafa and Rodero, Ivan and Devarakonda, Aditya},
journal={Computing in Science \& Engineering},
volume={15},
number={4},
pages={10--18},
year={2013},
doi={10.1109/MCSE.2013.49},
url={https://doi.org/10.1109/MCSE.2013.49}
}